Jessica has been awarded a 2025 Guggenheim Fellowship by the John Simon Guggenheim Memorial Foundation. The fellowship is one of the most prestigious... Read More
Catherine was supported by the SFI-NSF student mobility programme to visit us for six weeks from early August to mid September. During... Read More
Jessica was recognized as a ScholarGPS Highly Ranked Scholar, placing her in the top 0.05% of scholars worldwide in the RNA-Seq... Read More
Tianyi received his Ph.D. and the Outstanding Ph.D. Student Award at the 2024 Department of Statistics and Data Science Commencement. Congratulations!... Read More
The Warren Alpert Computational Biology and AI Network Fellowship will support Christy Lee and Pan Liu to attend the Computational Genomics Summer Institute for two years and provide... Read More
Congratulations to Guan’ao Yan for receiving the the UCLA Dissertation Year Fellowship!... Read More
In this JASA paper, we generalized the squared Pearson correlation to capture a mixture of linear dependences between two real-valued variables,... Read More
In collabortion with Dr. Lucy Xia at HKUST, Christy co-developed scDEED for detecting dubious 2D embeddings by non-linear dimension reduction methods (such as t-SNE and UMAP)... Read More
Guan’ao developed scReadSim, a single-cell RNA-seq and ATAC-seq read simulator that allows user-specified ground truths and generates synthetic sequencing reads (in... Read More
Congratulations to Xinzhou! https://grad.ucla.edu/life-at-ucla/events/2023-postdoctoral-scholars-mentors-awards-ceremony/... Read More
The JXTX Foundation and Cold Spring Harbor Laboratory announced the 2023 Genome Informatics Scholarship. JXTX and CSHL will provide travel... Read More
Congratulations to Kexin and Heather!... Read More
Our group members won multiple awards. Congratulations to all! Dongyuan received the UCLA Dissertation Year Fellowship. Guan’ao received UCLA Department of Statistics’ inaugural... Read More
Dongyuan developed scDesign3, the latest version of our simulator for single-cell and spatial omics data. The work was published in Nature Biotechnology.... Read More
Qingyang Wang was selected to receive the National Science Foundation (NSF) Graduate Research Fellowship. This fellowship will provide Qingyang with three... Read More
Jessica received the Overton Prize from the International Society of Computational Biology (ISCB). The Overton Prize was established by the... Read More
Jessica won one of the 2023 COPSS (Committee of Presidents of Statistical Societies) Emerging Leader Awards (https://community.amstat.org/copss/awards/leadership-academy). This award recognizes the talents,... Read More
The JXTX Foundation and Cold Spring Harbor Laboratory announced the 2023 Biology of Genomes Scholarship. JXTX and CSHL will provide... Read More
In collaboration with Chaorong Chen in Dr. Wei Li’s lab at UCI, Guan’ao won the 2022-2023 Interdisciplinary Opportunity Award at the UCI Center for... Read More
Chihao, a former visiting Ph.D. student from Dr. Shihua Zhang’s lab, developed the information-theoretic classification accuracy (ITCA), a criterion to guide... Read More
Thanks to the collaboration with Dr. Wei Li’s lab at UC Irvine, Heather wrote this article to compare PCA with SVA, PEER, and HCP for... Read More
Christy Lee was selected to receive the National Science Foundation Research Traineeship (NRT) “Modeling and Understanding Human Behavior: Harnessing Data from Genes... Read More
Our project “Enhancing Rigor and Reliability of Single-Cell Data Science” received the Chan-Zuckerberg Initiative Single-Cell Biology Data Insights Cycle 1... Read More
Congratulations! Kexin received the UCLA Dissertation Year Fellowship.... Read More
Guan’ao received the award at the 2022 Department of Statistics Commencement. Congratulations Guan’ao!... Read More
The Harvard Radcliffe Institute Fellowship Program, now in its 22nd year, offers scholars and practitioners in the arts, humanities, journalism,... Read More
Thanks to the collaboration with Dr. Wei Li’s lab at UC Irvine, Yumei (UC Irvine) and Xinzhou co-wrote this article about inflated false discovery... Read More
Our undergraduate student Zhengtong Liu was selected into the UCLA Applied and Computational Mathematics REU Program Summer 2022. Congratulations Zhengtong!... Read More
Ruochen, Tianyi, and Dongyuan co-wrote this review article about the zero-inflation controversy in the single-cell RNA-seq field. In particular, we clarify statistical and... Read More
In the podcast, Jessica describes common statistical pitfalls in genomic data analysis & the statistical reasoning required to correct these mistakes.... Read More
Xinzhou and Yiling developed Clipper, a general statistical framework for controlling FDR in high-throughout genomics data analysis. Clipper does not require high-resolution p-values, thus... Read More
Dongyuan’s PseudotimeDE poster (attached) was selected among the top 5 posters at the QCBio 2021 Retreat. Congratulations to Dongyuan! PseudotimeDE_poster... Read More
In the podcast, Jessica discusses her paper “Statistical Hypothesis Testing versus Machine Learning Binary Classification”. She noticed several high-impact cancer research... Read More
Yiling Elaine Chen will join Dr. Wei Li’s lab at UC Irvine as a postdoctoral researcher. Ruochen Jiang will join Veracyte Inc. as a bioinformatics scientist.... Read More
Ruochen developed mbImpute, an imputation method for microbiome sequencing count data. The work was published in Genome Biology. Congratulations!... Read More
Kexin Li, Dongyuan Song, and Guan’ao Yan were selected to receive the UCLA Summer Mentored Research Fellowship. Congratulations!... Read More
Chris Dong was selected to receive the National Science Foundation Research Traineeship (NRT) “Modeling and Understanding Human Behavior: Harnessing Data from Genes... Read More
Nan (Miles) received his Ph.D. in statistics in May 2021. He will join the Department of Mathematics and Statistics at Loyola University... Read More
Tianyi developed scDesign2, a statistical simulator that uses a copula-based probabilistic model to generate single-cell gene expression counts with gene correlations... Read More
In collaboration with Dr. Xin Tong, Jessica and Yiling developed the classical criterion (CC) and the Neyman-Pearson criterion (NPC) for model-free marginal feature ranking in... Read More
Dongyuan developed PseudotimeDE, a statistical method that infers differentially expressed (DE) genes along cell pseudotime. PseudotimeDE considers the uncertainty of pseudotime... Read More
Heather received the iDiscover Predoctoral Fellowship (https://cvdatascience.dgsom.ucla.edu/pages/positions). Congratulations!... Read More
Yidan received her Ph.D. in March 2021. She will join the Department of Statistics and Applied Probability at UC Santa Barbara as a... Read More
Miles conducted the first, systematic benchmark study of computational doublet-detection methods for single-cell RNA sequencing data. The study was published in Cell... Read More
Jessica was honored to be selected as one of the MIT Technology Review 35 Innovators Under 35 in the China... Read More
In the interview, Jessica described the AIDE method for discovering novel isoforms from short RNA-seq reads with confidence.... Read More
Episode: Genomic processes described using biology and statistics... Read More
Jessica received this award to support her collaboration with Dr. Mark Biggin and Dr. Wendy Gilbert in advancing fundamental understanding of translational control. For... Read More
Vivian developed a statistical method AIDE, the first mRNA isoform discovery method that enables the control of false isoform discoveries from short... Read More
Heather was selected to receive the National Science Foundation Research Traineeship (NRT) “Modeling and Understanding Human Behavior: Harnessing Data from Genes to... Read More
Vivian developed a statistical simulator scDesign for assisting the design (platform, number of cells, total sequencing depth, number of batches, etc.) of scRNA-seq... Read More
Yiling received the award at the 2019 Department of Statistics Commencement. Congratulations Yiling!... Read More
Vivian received her Ph.D. and the Most Outstanding Statistician Award at the 2019 Department of Statistics Commencement. She will join the Department... Read More
Xinzhou and Haowen developed a computational method EpiAlign for comparing chromatin state sequences from epigenomic data. Other current and former group members including Lingjue, Vivian, and... Read More
Zahra developed a novel generative model for bipartite networks with node covariates. The model assumes a matched community structure between two... Read More
Jessica received the Faculty Early Career Development (CAREER) Award from the National Science Foundation. [ NSF Award Page ]... Read More
Vivian and Jessica wrote a review article about statistical modeling of RNA-sequencing (RNA-seq) data at four leveles: sample-, gene-, isoform-, and exon-levels, all of which have... Read More
Wei Vivian Li presented her scImpute work and received the the Pearl Cohen Poster Award on the 1st annual UCLA Bioscience Innovation Day. Congratulations Vivian!... Read More
Yiling is the only international Ph.D. student who received the Biomedical Big Data (BBD) Training Grant, supported by NIH-NCI T32LM012424 and... Read More
Ruochen Jiang won the Most Outstanding Masters Student Award at the UCLA Department of Statistics Commencement 2018. Congratulations Ruochen!... Read More
Jessica received the 2018 International Chinese Statistical Association (ICSA) Conference Junior Researcher Paper Award for the manuscript titled “Budget-Constrained Feature Selection for... Read More
Wei Vivian Li received the Dissertation Year Fellowship. Congratulations Wei (Vivian)!... Read More
Jessica was named as one of the six inaugural Johnson & Johnson WiSTEM2D (Women in Science, Technology, Engineering, Mathematics, Manufacturing,... Read More
[ UCLA News ] Vivian and Jessica published an article on Nature Communications about a statistical method scImpute for imputing missing gene expression values due to dropout events in single-cell RNA-sequencing (scRNA-seq) data.... Read More
Vivian and Jessica published an article on The Annals of Applied Statistics about a statistical method MSIQ for more accurate and robust estimation of messenger RNA (mRNA) isoform abundance... Read More
Jessica was named as one of the 2018 Sloan Research Fellows. [ Sloan Foundation Announcement ] [ New York Times ] [ University of... Read More
Jessica and two collaborators (Dr. Xin Tong at USC and Dr. Yang Feng at Columbia) published an article on Science Advances about an umbrella algorithm to implement general... Read More
Xinzhou and Kexin were named the best performers in the conference round of the NCI-CPTAC DREAM Proteogenomics Challenge (Subchallenge 1) and presented at the RECOMB/ISCB Conference on... Read More
Jessica and Dr. Biggin published an article on Nucleic Acids Research about using statistics to quantitate translational control in yeast, adding a new work to their line of... Read More
Zahra received her Ph.D. in Statistics. Her dissertation title is “Community Detection in Networks with Node Covariates.” Surui received his M.S. in... Read More
Jessica and Dr. Zhi John Lu’s lab published an article on Nucleic Acids Research about large-scale mapping of mammalian transcriptomes by TROM and identification of conserved genes... Read More
Jessica and co-author Dr. Xin Tong wrote a chapter in the book Big Data Analytics in Genomics published by Springer.... Read More
[paper link] [software link]... Read More
Zahra Razeee received the Dissertation Year Fellowship. Congratulations Zahra!... Read More
Jason Mao, Yiling Chen and Yimeng Jia graduated from UCLA and receive their Bachelor’s degrees. Congratulations!... Read More
We had two papers accepted by APBC 2016 and published on BMC Genomics: the NMFP paper by Yuting and Jessica, and the EPOM paper by Wei, Zahra and Jessica.... Read More
Wei Vivian Li won the Most Promising Computational Statistician Award at the UCLA Department of Statistics Commencement 2015. Congratulations Wei! Statistical... Read More
Jessica published a perspective with Dr. Mark Biggin, titled “Statistics requantitates the central dogma” on Science.... Read More