Dissecting gene expression heterogeneity: generalized Pearson correlation squares and the K-lines clustering algorithm
77. Li, J.J., Zhou, H.J., Tong, X., and Bickel, P.J. (2024). Dissecting gene expression heterogeneity: generalized Pearson correlation squares and the K-lines clustering algorithm. Journal of American Statistical Association 119(548):2450-2463. [ SOFTWARE ] | [ PDF ]
A genome-wide spectrum of tandem repeat expansions in 338,963 humans
76. Cui, Y., Ye, W., Li, J.S., Li, J.J., Vilain, E., Sallam, T., and Li, W. (2024). A genome-wide spectrum of tandem repeat expansions in 338,963 humans. Cell 187(9):2336-2341. | [ PDF ]
scDEED: a statistical method for detecting dubious 2D single-cell embeddings
75. Xia, L.*, Lee, C.*, and Li, J.J. (2024). Statistical method scDEED for detecting dubious 2D single-cell embeddings and optimizing t-SNE and UMAP hyperparameters. Nature Communications 15:1753. (Featured in Nature Communications Editors’ Highlights) [ Nature Methods: Seeing data as t-SNE and UMAP do ] [ SOFTWARE ]
scDesign3 generates realistic in silico data for multimodal single-cell and spatial omics
73. Song, D., Wang, Q., Yan, G., Liu, T., and Li, J.J. (2024). scDesign3 generates realistic in silico data for multimodal single-cell and spatial omics. Nature Biotechnology 42:247-252. [ SOFTWARE ] [ PDF ]
Hierarchical Neyman-Pearson classification for prioritizing severe disease categories in COVID-19 patient data
A Python Package itca for Information-Theoretic Classification Accuracy: A Criterion That Guides Data-Driven Combination of Ambiguous Outcome Labels in Multiclass Classification
scReadSim: a single-cell RNA-seq and ATAC-seq read simulator
71. Yan, G., Song, D., and Li, J.J. (2023). scReadSim: a single-cell RNA-seq and ATAC-seq read simulator. Nature Communications 14:7482. [ SOFTWARE ] [ PDF ]
Exploring the optimization of autoencoder design for imputing single-cell RNA sequencing data
70. Xi, N.M. and Li, J.J. (2023). Exploring the optimization of autoencoder design for imputing single-cell RNA sequencing data. Computational and Structural Biotechnology Journal 21:4079-4095.